Accommodating covariates in receiver operating characteristic analysis


PSA and age values of 125 patients who were examined prostate biopsy with pre-diagnosis of prostate cancer in Gaziosmanpasa University Faculty of Medicine Department of Urology at the years of 2005 to 2007.

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Results: According to the simulation study, if biomarker indicators in healthy group are constant and are lower or equal in healthy group than/to disease group, both adjusted AUC (Adj AUC) and AUC have small values and, no significant difference was found between them.

The AUC was significantly larger when the biomarker indicators in disease group were higher.

We also illustrate how these measures can be applied using the evaluation of a hypothetical new diagnostic test as an example.

A diagnostic classification test typically yields binary, ordinal, or continuous outcomes.

Topics addressed include: Written for any statistician interested in learning more about ROC curve methodology, the book assumes readers have a basic understanding of regression procedures and moderate familiarity with Base SAS and SAS/STAT.